NFL Betting

The NFL is the most popular sport in the U.S. and continues to grow its global audience. It’s also immensely popular among sports bettors who carefully examine NFL odds every week.  

The NFL regular season lasts 18 weeks and includes up to 16 weekly games. At the end of the season, a 14-team, single-elimination playoff culminates in the Super Bowl, the biggest sporting event in the U.S. every year. 

For every NFL game, there are several betting markets. This gives you several angles for examining NFL betting odds and placing wagers. Let’s take a closer look at how NFL odds work, the various betting markets available on American football, and how to bet responsibly at talkSPORT BET Sportsbook.  

Handicap Bets

Handicap bets are known as point spreads in the United States, and they’re the most common way of betting on the NFL.  

Placing a handicap bet on a game is a way of levelling the playing field and getting an equal amount of betting on both sides.  

For example, one NFL team might be favoured by 5.5 points. This means they must win the game by six points or more for point-spread bets on that team to win.  

In contrast, bets on the underdog will pay out if that team wins the game or loses by five points or less. Most of the time, each side of the bet will have odds of 10/11. This means that a bet of £100 would have a payout of £190.91, meaning a profit of £90.91. 

Moneyline

Betting on an NFL game using the moneyline takes the point spread out of the equation. A moneyline bet is only concerned with the winner of the game. However, this means that the odds each NFL team receives are often unbalanced. For instance, a team that’s favoured might have odds of 2/5, meaning that a £100 bet results in a £140 payout.

The underdog in that game may have odds around 2/1, meaning a £100 bet results in a £300 payout. Since the underdog winning is less likely to happen, the payout is larger while the safer bet on the underdog comes with a smaller payout.

Totals (Over/Under)

In some cases, NFL betting odds ignore winners and losers and focus on the total number of points scored in a game. This is called totals or over/under-betting.  

For each NFL game, a total points line is set (for instance, 45.5). You can then bet on whether over or under this number of points will be scored in the game.  

Similar to point spread bets, total bets often come with odds around 10/11, so a bet of £100 typically has a payout of around £190.91. 

Outright Betting

In addition to betting on specific games, NFL betting odds are available for future outcomes, which is also known as outright betting in the United Kingdom.  

These are bets placed on a team accomplishing something specific or reaching a milestone. Backing a team to win the Super Bowl is the easiest way to place an outright NFL bet, but you can also bet on divisional and conference winners, as well as the season MVP.  

Since there are multiple teams in contention to win the Super Bowl during the season, the odds tend to be more lucrative. One of the top favourites might have odds around 5/1, meaning a £100 winning bet will pay £600. 

A team that’s more of a dark horse to win the Super Bowl could have 20/1 odds, meaning a £100 winning bet would payout £2,100. 

Prop Bets

Prop bets are a slightly more complicated type of NFL odds. These are wagers made on events that happen within a game rather than the outcome of the game itself. This can create an almost endless list of NFL betting odds for every game on the schedule. There can be game props, team props, and even player props.

In an NFL game, there could be prop bets for whether the game will go to overtime, whether any team will score at least 30 points, whether every quarter will have a touchdown, among many other possibilities.

There could also be prop bets for the first and last team to score in a game. Team props often refer to the total points a specific team will score in the game or in a particular half or quarter. There can also be props for how many touchdowns or field goals a team will score in a game.

Finally, player props also offer many possibilities during NFL games. Similar to totals on the number of points scored in a game, there are over/under numbers assigned to the total number of passing, rushing, or receiving yards a specific player will have in a game.

Similarly, there are also over/under values for a quarterback’s pass attempts or pass completions in a game or a player’s rush attempts or receptions. Player props can also include bets on a specific player to score a touchdown during the game.

The Philadelphia Eagles are the NFL Champions after winning Super Bowl LIX at the end of the 2025 season.  

In a meeting of the two teams from Super Bowl LVII in 2023, the Eagles defeated the Kansas City Chiefs 40-22 in New Orleans to win their first Super Bowl since 2018. If the Chiefs had won in 2025, they would have secured their third consecutive NFL Championship, but it wasn’t to be. 

If you want to base your NFL outright betting strategy on the previous winners, here are the last ten winners and runners-up of the NFL to help you make your selections:  

As the defending champions, the Philadelphia Eagles are the team to beat in the 2025/26 NFL season. Alongside 2025’s losing finalist, Kansas City, the Eagles are joint favourites to win Super Bowl LX.  

The Buffalo Bills and Baltimore Ravens are the next in line, while you can also get short odds on the Detroit Lions to go the distance this season. Check out the latest NFL Super Bowl odds before placing outright bets at talkSPORT BET. 

You can pick your Super Bowl winner at any stage of the season, but when you bet earlier, you can lock in great value odds.  

Here at talkSPORT BET, you can find a full listing of American Football odds and a list of Super Bowl odds for Super Bowl LX. Also, we have betting odds for other sports, including basketball odds and baseball odds.